Microfluidic chip technology integrates the basic operational units of sample preparation, reaction, separation, detection and more involved in biological, chemical and medical analysis processes onto a micro-scale chip to automatically accomplish the entire analysis process.
This technology includes platinum resistance chips, pressure sensor chips, electrochemical sensor chips, micro/nano-reactor chips, microfluidic fuel cell chips, micro/nano-fluid filtration chips, and more.
Microfluidic chips are currently the main focus of development in micro-total analysis systems
Microfluidic chip analysis uses a chip as an operational platform, while relying on analysis chemistry and micro-electro-mechanical processing technology, with micro-channel networks as structural features and life sciences as the primary application objective. Its goal is to integrate all the functions of the entire laboratory, including sampling, dilution, reagent addition, reaction, separation, detection, etc. on a microchip, which can be reused multiple times.
Microfluidic chips are the main platform for implementing microfluidic technology
The device is mainly characterized by its effective structure for accommodating fluid (channels, reaction chambers and other functional components), which is at least on a micron scale on one dimension. Due to the micron-level structure, fluid exhibit unique characteristics and performance different from those at the macro scale, leading to unique analytical performance.
Characteristics and advantages of microfluidic chips
Microfluidic chips have controllable liquid flow, minimal consumption of samples and reagents, and speeds up to tens or even hundreds of times faster than traditional analyses. They can analyze hundreds of samples in just a few minutes or even shorter time and can realize sample pre-processing and the entire analysis process online.
The ultimate goal of its application is to achieve the chip laboratory of a micro-total analysis system, and its current focus of development is primarily in the field of life sciences. Innovation in this field is mainly focused on separation and detection systems. However, there are many weak areas related to how to introduce actual sample analysis into microfluidic chips, such as sample introduction, sample exchange, pre-treatment, etc. Its development relies on interdisciplinary development.
The bio-chips widely believed by the media, such as gene chips and protein chips, are only special types of microfluidic chips with zero micro-flow, with very limited functionality. Microfluidic chips have a wider range of types, functions, and applications, and can be developed into analytical systems such as bio-computing, gene and protein sequencing, mass spectrometry and chromatography, thus becoming an extremely important technological basis for systems biology, especially systems genetics.
The Benefits of Preimplantation TestingApril 16, 2025What Is Preimplantation Testing?Preimplantation testing refers to the chromosomal or specific gene testing of embryos before implantation. This is done to select embryos that do not carry genetic defe...view
Introduction to Microarray Chip Analysis TechnologyApril 10, 2024Microarray chip analysis technology, as an important innovation in the field of modern biotechnology, plays an increasingly important role in the fields of genomics, proteomics, and disease diagnosis ...view
The Impact of DNA Genome Sequencing on Cancer Research and TreatmentJuly 18, 2024Cancer remains one of the most formidable challenges in medical science. As we continually seek innovative solutions to understand and combat this complex disease, DNA genome sequencing has proven to ...view
Application of Genome Sequencing Technology in Newborn ScreeningNovember 13, 2024Newborn screening is a successful public health initiative that prevents diseases and reduces mortality through early diagnosis and disease management. In the era of precision medicine, the expansion ...view
What is IVF Preimplantation Genetic Testing (PGT)?June 20, 20221. What is Preimplantation Genetic Testing (PGT)?Preimplantation genetic testing (PGT) is a method of screening some cells from an embryo and detecting related genetic and chromosomal disorders. This ...view